Show this safety data sheet msds to the doctor in attendance. This protocol describes chemical mutagenesis of male mice using N- ethyl- N- nitrosourea ( ENU), which is the most efficient method for obtaining mouse mutations in phenotype- driven screens. If breathed in, move person msds into fresh air. These alkylators are directly reactive with DNA sheets do not require metabolic activation for their activity. Empirical Formula ( Hill Notation) C 3 H 7 N 3 O 2. Many small alkylating agents including dimethyl , diethyl nitrosamine, N- ethyl- N′ msds - nitrosourea, N- methyl- N′ - nitrosourea, , 2- dimethyl hydrazine, 1, sheets are potent carcinogens mutagens. N ethyl n nitrosourea msds sheets.
N- Ethyl- N- nitrosourea has a preferential transplacental a single intravenous , neonatal action intraperitoneal injection inducing an almost 100% incidence of neural neoplasms. Transplacental carcinogenesis by N- ethyl- N- nitrosourea provides an ideal experimental model in which the sequential development of brain tumours can be studied. N- Nitroso- N- methylurea is a nitrosourea sheets compound with alkylating carcinogenic, mutagenic properties. It is also toxic at high doses. N- Nitroso- N- ethylurea ISOPAC sheets ® Synonym: ENU, N- Ethyl- N- sheets nitrosourea CAS Number. Molecular Weight 117. PubChem Substance ID. N- ethyl- msds N- nitrosourea: N- ethyl- N- nitrosourea: 759.
For a given gene in mice, msds ENU can induce 1 new mutation in every 700 loci.
Search results for N- methyl- N - nitrosourea at Sigma- Aldrich. Compare Products: Select up to 4 products. * Please select more than one item to compare. Chemsrc provides N- ethyl- N- nitrosourea( CAS# : MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of N- ethyl- N- nitrosourea are included as well.
n ethyl n nitrosourea msds sheets
CAS Number Search. In the mouse, random mutagenesis with N- ethyl- N- nitrosourea ( ENU) has been used since the 1970s in forward mutagenesis screens. However, only in the last decade has ENU mutagenesis been harnessed to generate a myriad of new mouse mutations in large- scale genetic screens and focused, smaller efforts.